The preliminary data released by George Institute for Global Health in the national Capital is indicating that obesity is highly prevalent amongst Indians with CKD, with over-representation of individuals with disproportionately enlarged waist lines, which is likely to take huge toll on their kidney function
High levels of Body Mass Index (BMI) and waist circumference play a key role in development and progression of Chronic Kidney Disease (CKD), preliminary data emerging from the Indian Chronic Kidney Disease (ICKD) study — an ongoing longitudinal study under Department of Biotechnology, Ministry of Science and Technology, has shown.
The preliminary data released by George Institute for Global Health in the national Capital is indicating that obesity is highly prevalent amongst Indians with CKD, with over-representation of individuals with disproportionately enlarged waist lines, which is likely to take huge toll on their kidney function. Worse still, women are more likely to be than men.
The preliminary analysis of data of over 1,500 patients with kidney disease recruited as part of the study showed the overall prevalence of obesity at 49 per cent, but the figure in women was a whopping 57 per cent. The data on abdominal obesity is even more alarming, with about 63 per cent of women and 48 per cent of men exhibiting waist circumference beyond the cut-offs accepted for the Asian population.
"The data confirms that there is high prevalence of obesity in patients with chronic kidney disease. The high prevalence of abdominal obesity among women is of particular concern," said Dr Vivekanand Jha, Executive Director of the George Institute for Global Health.
Doctors claim that obese people are twice as likely to develop kidney disease compared to those with normal weight. Obesity also increases the likelihood of development of complications, such as cardiovascular disease. Currently, there is no data on this relationship from India. The exact mechanisms whereby obesity may cause development and worsening of CKD also remain unclear.
"Some of the deleterious renal consequences of obesity may be mediated by co-morbid conditions such as diabetes or hypertension, but there are also effects of adiposity that impact the kidneys directly resulting in pathological changes," said Dr Jha.
"We hope to explore the link between kidney disease and central or abdominal obesity that is prevalent in Indians and is proven to be particularly harmful," he said.
The Department of Biotechnology is conducting a long-term population based ICKD study on Indian patients with moderate kidney failure.
As per the data from the Global Burden of Disease Study 2013, India is just behind the US and China in terms of the number of obese people. The US is number one with 13 per cent, while China and India account for 15 per cent with 46 million and 30 million obese people respectively.
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