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Multi-drug resistant organisms causing deadly infections spreading in community

A recent study by the researchers have found out that classically ‘hospital‘ strains which were drug resistant with high mortality are now spreading in community too.

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A recent study by the researchers have found out that classically ‘hospital‘ strains which were drug resistant with high mortality are now spreading in community too. This means the bacteria causing infections which were mostly found in the hospitals are now seen in community as well. So, be it your home, office or any other space, the resistance bacteria is seen everywhere.

The retrospective study conducted by researchers at Sir Ganga Ram hospital was done on 201 patients who did not come into contact with any health care facility in last three months or more. Infections due to multidrug resistant organisms have become a serious health concern worldwide.

According to the experts, the present study was conducted to investigate the spectrum of microbial resistance pattern in the community and their effects on mortality.

“The results are extremely worrying. The incidence of resistance among bacteria has increased and is  spreading in the community. The distinction between community-acquired and hospital-acquired infections is becoming increasingly blurred. The main reasons for this are the spread of classically 'hospital' strains, particularly resistant Klebseilla and E. Coli, into the community and vice versa, and the repeated admissions of individuals to hospitals with long standing underlying diseases,” said Dr Sumit Ray, Author of the study  & Vice-Chairman, Department of Critical Care, Sir Ganga Ram Hospital.

"Increased use of anti-biotics in animals and by humans and changing environment are few reasons for the spread of this resistance bacteria in the community. “Many a time patients who go back from the hospital carries back a little bit of the infection to the community,” added Dr Ray.

Of the 5309 patients screened from the database admitted to ICU, 3822 (71.9 per cent) were infected on the day of admission or within 48 hours of admission. . Of the suspected infected patients, 37.9% (1452/3822) had positive microbial isolates; 13.8% (201/1452) of these culture positive patients were direct admissions from community with no documented contact with any health care facility in last 3 months and enrolled into the study.

Out of 5309 patients enrolled; 3822 had suspected clinical infection on admission with 1452 patients growing positive microbial cultures. Among these, 201 bacterial strains were isolated from patients who had community acquired infections. The World Health Organization and Centre for Disease Control and Prevention guidelines have also emphasized the need of exploring incidence and associated risk factors which contribute to  multidrug resistance.

“In addition, the contribution of antibiotic resistance in the community through easily available antibiotics often used without medical supervision has resulted in an increasing reservoir of potential infections. The resistance to high end antibiotics by organisms contracted by patients in the community resulting in high mortality, seen in our study, is a cause for worry and needs further research and proper action plan,” added Dr Ray.

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