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65 doctors pull off India's biggest domino kidney transplant

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The nation’s biggest domino kidney transplant was successfully performed in the city on Saturday. The swap procedure, which involved six donors and six recipients, was conducted in three hospitals. Of the six transplant surgeries, three were done at Bombay Hospital and two at Hiranandani, while one was carried out at Hinduja. Sixty-five doctors pulled off the domino transplant.

The complex transplant involved a series of surgeries in which each of the six donors gave an organ to a recipient not related to him/her, while a donor’s relative needing an organ got it from a recipient’s kin. Since legal issues were involved, authorities concerned had obtained necessary approvals from the government.

Nephrologist Dr Mukul Shetye from Hiranandani Hospital, who was part of the domino procedure, said, “Two pairs were operated at our hospital. By 2 pm, all operations were done in three hospitals. Everything went smoothly.”

Dr Shetye said there were other parameters to gauge the success of the transplant. “One of them is after transplanting the kidney on a patient, he or she should immediately pass urine like a normal person. Within 24 hours after the operation, a patient should pass 8-10 litres of urine.”

In kidney patients, the creatinine levels are as high as 6-8 mg/dl, but after the surgery it drops by 50% and soon normalizes to around 0.5 – 1 mg/dl. Dr Shetye added, “The donors will be discharged after a week, but the recipient will be required to stay in the hospital for at least 10-12 days.”

Another nephrologist Dr Rajesh Kumar from the same hospital said such swap surgeries are pretty common in the US and its success has been reported in several journals. Kumar said, “The interesting thing about domino kidney transplant is that despite blood groups not matching, those in need are able to get the organ. In this case, all the credit goes to the Apex Swap Transplant Registry that addresses the issue of mismatch in blood groups or tissues.”

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