Now, women with Polycystic Ovary Syndrome can be blessed with motherhood with the help of the latest treatment.
Now, women with Polycystic Ovary Syndrome (PCOS) can be blessed with motherhood with the help of the latest treatment.
More and more experts in the city are practising and recommending a new technology —in-vitro maturation (IVM) — instead of the conventional in-vitro fertilisation (IVF). With IVM, women need to have fewer drugs. An entire cycle of treatment costs around Rs1 to Rs1.5 lakh.
Even as the first Indian IVM baby was produced in Bangalore in 2003, the technique hasn’t been picked by many fertility centres. However with the increasing prevalence of PCOS in women, experts are now exploring this new technology.
IVF specialists Dr Hrishikesh Pai and Dr Nandita Palshetkar of Bloom IVF clinic have treated five women in past two months. “Two patients are already into their sixth week of pregnancy,” said Pai.
“The best part is that the heavy duty drug approach can be avoided in IVM. Women get negligible or very low dose of hormone drugs which is needed to mature the eggs,” said Pai, who learnt the IVM technique from Canada six months ago.
IVM involves removing immature eggs from a woman’s ovaries and maturing them in laboratories before fertilising them with a man’s sperm. “Women with PCOS tend to produce too many eggs when their ovaries are stimulated with IVF drugs,” said Palshetkar, who is also a consultant with Lilavati and Fortis hospitals. “In IVM, these drugs are avoided and are instead used as a media to mature the eggs in a laboratory dish.”
Citing an example of a 27-year-old woman from Navi Mumbai, Palshetkar said she produced as many as 30 eggs during the IVF treatment. “We abandoned the cycle and started a fresh one, but the same thing happened. Finally, we did the IVM technique and the eggs were removed before maturation and it worked.”
Experts say this technique may also be a boon for women suffering from breast cancer as due to fewer drugs, the cancer will not be aggravated.
According to gynaecologist Dr Duru Shah, women with PCOS may develop complications like blood clots, abdominal distension, etc, during IVF. “Such complication can be avoided through IVM,” Shah said.
However, not all experts are in favour of the technique. “Be it IVF or IVM, the success rate is finally measured through the percentage of pregnancies. The results of IVM are not that good,” said Dr Kedar Ganla, fertility consultant, Hiranandani Hospital.
According to Ganla, extraction of eggs is a difficult process and the implant failure rate is also very high.
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