Cancer susceptibility in families

Studying thousands of people, researchers at The University of Texas Madison, Anderson Cancer Centre have documented a 25 per cent increased risk of developing one of a number of cancers in first-degree relatives of lung cancer patients who have never smoked compared to families of people who neither smoke nor have lung cancer.
Researchers say their study, one of the largest ever done and the only one to include both men and women, strongly suggests that these lung cancer patients and their affected relatives share an inherited genetic susceptibility to cancer development.

Such marked cancer susceptibility also likely explains why patients in this study, who never smoked but might have been exposed to secondhand smoke, developed lung cancer in the first place, says the study author Olga Gorlova.