Stan Wawrinka's campaign for a second Australian Open title stepped up a gear on Sunday as the hard-working Swiss fended off Italian journeyman Andreas Seppi 7-6(2) 7-6(4) 7-6(4) to reach his fourth quarter-final at Melbourne Park.

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The 2014 champion has done it tough in the opening week, but despite the tight scoreline, he was rarely threatened by 89th-ranked Seppi on a sunny afternoon at Margaret Court Arena.

With top seed Andy Murray crashing out only minutes before the win, Wawrinka's chances of grabbing a fourth grand slam title have been given a huge boost and he is now the highest seed in the top half of the draw.

Wawrinka next faces Dan Evans or Jo-Wilfried Tsonga for a place in the semi-finals.