Maria Sharapova faces up to six weeks out of action due to an elbow injury, organisers of next week's Sony Ericsson Open said on Wednesday.
The three-times grand slam champion was due to compete in the event at Key Biscayne, Miami but an MRI scan revealed a bone bruise on her right elbow.
Organisers said in a statement that the Russian, who won earlier this year in Memphis but had an early exit at Indian Wells on Sunday, was expected to miss three-to-six weeks of competition.
World number two Dinara Safina and 2008 Sony Ericsson men's champion Nikolay Davydenko have also withdrawn from this year's Miami event. Russian Safina is suffering a back injury while Davydenko has a left wrist fracture.
Five-times champion Serena Williams and her sister Venus headline the women's field while Roger Federer and Rafa Nadal top a strong men''s field.
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