Asian shares slipped on Tuesday as a United States holiday robbed markets of momentum, while the euro hit a fresh one-year low on uncertainty over the European Central Bank's policy decision later this week.
Spreadbetters expected an effectively flat open for Europe, with Britain's FTSE, Germany's DAX and France's CAX forecast to open about 0.1% higher.
MSCI's broadest index of Asia-Pacific shares outside Japan lost 0.6% after managing to carve out gains on the previous day.
With United States markets closed for Labor Day, investors in Asia were somewhat subdued. The mood was also tempered by persistent geopolitical concerns and anaemic manufacturing surveys in Asia and Europe showing pockets of weakness in the global economy.
Tokyo's Nikkei bucked the trend and rose 1.2%, with a planned cabinet reshuffle by Prime Minister Shinzo Abe helping fuel reform hopes.
The dollar, boosted by the flagging euro and gains in Tokyo shares that dented the appeal of the safe-haven yen, rose to a seven-month high of 104.87 yen.
"The dollar's gains are driven by actual flows, such as options-related buying. The market is also keeping an eye on the rise in equities," said Shinichiro Kadota, chief Japan FX strategist at Barclays Bank in Tokyo.
Immediate focus was on the ISM's report on United States manufacturing due later in the day, which might point to the United States phasing out quantitative easing just as the ECB contemplates its adoption.
The euro slipped to a fresh one-year low of $1.3115.
The common currency was expected to remain under pressure ahead of Thursday's European Central Bank policy meeting.
While many market participants do not expect the ECB to take major easing steps this week, a few are seen braced for new policy measures. Further central bank easing is considered a matter of when and not if in the face of risks to euro zone growth posed by the Ukraine conflict and stubbornly low inflation.
"This week may start to mark the biggest shift in global monetary policy since 'Abenomics' went into full steam on the appointment of Haruhiko Kuroda to head up the BOJ," equity strategists at Jefferies wrote in a note to clients.
The decline in European headline inflation rates, collapse in German bund yields, and the call by the president of the ECB for 'growth friendly' fiscal policy suggests that Europe is finally moving towards quantitative easing, they said.
The Australian dollar showed little reaction to the well-anticipated decision by the Reserve Bank of Australia to keep its cash rate at a record low 2.5% for the 12th consecutive meeting.
The Aussie was down 0.4% at $0.9296 after brushing a one-week low of $0.9285.
In commodities, Brent crude held steady below $103 a barrel on Tuesday, with new unrest in OPEC oil producer Libya balanced by concerns of slowing oil demand growth due to weak economic recoveries in China and Europe.
Palladium hovered near a 13-1/2 year high of $910 an ounce hit overnight on fears that possible Western sanctions against Russia over the Ukraine crisis could hit supply from the world's top producer of the metal, while gold nudged higher.
Spot palladium last traded at $904.50 an ounce. Russia accounted for more than 40% of global palladium supply last year.