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I want Britain's first three-parent baby, mom of disabled child appeals to MPs

A British mother who is in line to be the first in the country to create a baby with three parents on Sunday appealed to lawmakers to change the law and allow her to give birth. Vicky Holliday, 38, is reluctant to have a second child with her partner Keith Newell after their first, one-year-old Jessica Newell, was born with a devastating disease caused by faulty mitochondrial DNA.

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A British mother who is in line to be the first in the country to create a baby with three parents on Sunday appealed to lawmakers to change the law and allow her to give birth. Vicky Holliday, 38, is reluctant to have a second child with her partner Keith Newell after their first, one-year-old Jessica Newell, was born with a devastating disease caused by faulty mitochondrial DNA.

Holliday is being treated by a British scientist who has spent 15 years developing a technique to use DNA from a second mother alongside her own nucleus and her partner's sperm. The result would be a baby free of the disease. It would take almost all its genetic characteristics from its mother and father but with extra material from a third parent that would then be passed to future generations, the Sunday Times reported.

Holliday's appeal to MPs came ahead of a vote on Tuesday on whether to amend the Human Fertilisation and Embryology Act to make the method legal. In her appeal, Holliday begged MPs to make Britain the first country to introduce legislation allowing the procedure.

"It's a very exciting moment," said Holliday, a management consultant in Buckinghamshire. "It would mean so much to us to be able to have a healthy child." "If MPs vote to allow the treatment it will not only be fantastic for us but help so many others too. When you're given the worst possible news it helps to have a little bit of hope," she said.

Mitochondria are self- contained units within the cell that produce its energy and have many other vital functions, which include producing hormones and other essential compounds. Supporters say the amount of DNA they contain is so small that any alterations will have only a small impact on the child.

However, critics counter that this is unproven. The change is being opposed by the Church of England. Jessica, Holliday's first child had seemed normal when she was born in December 2013.

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