Robert Pattinson has branded fans of Twilight as having some "kind of mental disorder" for camping out in the cold to catch a glimpse of him and co-star Kristen Stewart in the freezing London air on Wednesday night.
Pattinson told frenzied fans at the final film's London premiere that the saga had ''changed everything'' about his life.
But he said he did not understand why they would go through such an ordeal to see him.
''It's very, very, very cold and I don't understand what kind of mental disorder you have," he said.
The arrival of the British actor and his co-stars Kristen Stewart and Taylor Lautner in Leicester Square was greeted with wild screaming and cheering from thousands of ''Twi-hards''.
Some 6,000 fans, some of who have camped since Saturday, packed the square. Many came from outside the UK, with fans from the USA, Dubai, Sweden, Norway and Hungary all amongst the crowd.
''(The reaction) makes me feel very foreign. It's really nice, it's really nice, especially after five years,” Pattinson said.
''They have stuck around, they're still camping out, I respect that. 'It's very, very, very cold and I don't understand what kind of mental disorder you have."
Pattinson told the crowds in an interview on a specially erected stage that the saga connected to people on a ''primal'' level.
''For me it's changed everything about my life. I don't even think I'd be acting if I wasn't doing this, or if I hadn't done the first one. It's crazy. The character and the whole experience combined for me,'' he said.
''It's definitely really created something which connects to people on a very fundamental level, it's like primal,” the 26-year-old added.