The blockbuster, starring Aamir Khan, Katrina Kaif and Abhishek Bachchan, raked in Rs 500 crores by making Rs 351.29 crores in India and Rs 150.06 crores abroad, according to the production house.
It is the third instalment of 'Dhoom' series.
The movie was helmed by Vijay Krishna Acharya and produced by Aditya Chopra.
'Dhoom 3', saw Abhishek and Uday Chopra reprising their roles as Jai Dixit and Ali Akbar, respectively, while actors Aamir and Katrina were seen as the antagonist duo.
The movie has surpassed the previous highest-grossing Bollywood film "Chennai Express" starring Shah Rukh Khan and Deepika Padukone.